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Another hormone important for growth, called insulin-like growth factor 1, or IGF-1. Has implications for the interpretation of the benefit of treatment in studies where the number of children with familial short stature in the controls or treated subjects is not known. Somatotropin was synthesized artificially in medical and sports practice. GHD Recurrence of pituitary adenoma and of craniopharyngioma were reported in one case each.

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